The best replacement for quake 4 is doom 3.

The best alternatives to quake 4 are rated as following:
★★★★★  doom 3
★★★  quake 3
★★  unreal tournament 3
★★  half life 2
★★  fear
★  quake live
  unreal tournament
  quake 2
  xbox 360 quake 4
  unreal tournament 2004
  f e a r
  quake wars

Your alternative for quake 4 is not listed? Suggest!
Speaking about quake 4, one probably shouldn't forget about quake 2.

Other search terms related to quake 4 and their ratings are:
★★★★★ quake 2
You have in mind a companion for quake 4 and it is not yet here? Propose!



Google Trends

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quake 4
doom 3
quake 3