The best replacement for quadro 6000 is k6000.

The best alternatives to quadro 6000 are rated as following:
★★★★★  k6000
★★★★  gtx 690
★★★★  k5000
★★★  firepro w9000
★★★  tesla c2075
★★  firepro v9800
★  tesla c2070

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quadro 6000
k6000
gtx 690