The best replacement for prazosin is clonidine.

The best alternatives to prazosin are rated as following:
★★★★★  clonidine
★★★★  doxazosin
★★★★  phenoxybenzamine
★★★  tamsulosin
★★★  flomax
★  terazosin
  phentolamine

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Google Trends

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prazosin
clonidine
doxazosin