The best replacement for polymyxin b is bacitracin.

The best alternatives to polymyxin b are rated as following:
★★★★★  bacitracin
★★★★★  colistin

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Speaking about polymyxin b, one probably shouldn't forget about trimethoprim.

Other search terms related to polymyxin b and their ratings are:
★★★★★ trimethoprim
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polymyxin b
bacitracin
colistin