The best replacement for oregano is marjoram.

The best alternatives to oregano are rated as following:
★★★★★  marjoram
★★★★★  basil
★★★★  thyme
★★★★  weed
★★★  dried
★★  ground oregano
★★  sage
★★  greek oregano
★  oregano leaves
★  parsley
★  fresh oregano
★  dried oregano
★  olive leaf extract
★  mexican oregano
★  oregano
★  origanum
★  oregano oil
★  fresh
★  olive leaf
★  rosemary
★  mediterranean oregano
★  tea tree oil
  natural factors oil of oregano
  italian oregano
  tea tree
  oregano leaf

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Google Trends

Scale is based on the average worldwide traffic of oregano in all years. Click on graph for more.