The best replacement for mydefrag is jkdefrag.

The best alternatives to mydefrag are rated as following:
★★★★★  jkdefrag
★★★★  ultradefrag
★★★★  defraggler
★★★  windows defrag
★★★  auslogics
★★  smart defrag
★  windows 7 defrag
★  smart defrag 2
★  diskeeper

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