The best replacement for midrin is fioricet.

The best alternatives to midrin are rated as following:
★★★★★  fioricet
★★★★  imitrex
★★★  prodrin
★★  maxalt
★★  fiorinal
★  butalbital
★  epidrin
  relpax
  axert
  zomig

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No companions for midrin have been suggested so far.
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