The best replacement for microsoft publisher is adobe indesign.

The best alternatives to microsoft publisher are rated as following:
★★★★★  adobe indesign
★★★★  frontpage
★★★  scribus
★★★  indesign
★★  microsoft word
★  pagemaker
★  print shop
★  adobe pagemaker
★  adobe illustrator
★  apple pages
  corel draw
  serif pageplus

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