The best replacement for memantine is donepezil.

The best alternatives to memantine are rated as following:
★★★★★  donepezil
★★  namenda
★  aricept
★  amantadine
  exelon

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Speaking about memantine, one probably shouldn't forget about donepezil.

Other search terms related to memantine and their ratings are:
★★★★★ donepezil
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