The best replacement for megadeth is metallica.

The best alternatives to megadeth are rated as following:
★★★★★  metallica
★★★★  slayer
★★  iron maiden
★★  pantera
★★  anthrax
★  dream theater
★  avenged sevenfold
★  slipknot
  black sabbath
  megadeath
  dissection
  judas priest
  metallica who is better
  testament
  megadeth

Your alternative for megadeth is not listed? Suggest!
Speaking about megadeth, one probably shouldn't forget about kerry king.

Other search terms related to megadeth and their ratings are:
★★★★★ kerry king
★★★ marty friedman
★★ cristina scabbia
★★ lacuna coil
★ david draiman
★ slayer
★ iron maiden
★ vinnie colaiuta
★ ellefson
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megadeth
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