The best replacement for manned is unmanned aircraft.

The best alternatives to manned are rated as following:
★★★★★  unmanned aircraft
★★★★★  unmanned space exploration
★★★★  unmanned
★  unmanned flight
★  unmanned airplanes
  unmanned exploration

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Google Trends

Scale is based on the average worldwide traffic of manned in all years. Click on graph for more.
manned
unmanned aircraft
unmanned space exploration