The best replacement for mame is jamma.

The best alternatives to mame are rated as following:
★★★★★  jamma
★★★★  mame32
★★★  kawaks
★★★  mess
★★  em
★★  injure
★★  sir
★  mameui
★  neo geo
★  final burn alpha
★  mame plus
★  seriously injure
★  kill
  arcade
  roms
  hurt
  pcb
  fba
  advancemame
  maim
  neoragex
  raine
  neogeo

Your alternative for mame is not listed? Suggest!
Speaking about mame, one probably shouldn't forget about kaillera.

Other search terms related to mame and their ratings are:
★★★★★ kaillera
★★★★ netplay
★★ xbox 360 controller
★ ps3 controller
tekken tag tournament
You have in mind a companion for mame and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of mame in all years. Click on graph for more.
mame
jamma
mame32