The best replacement for magic penetration is ability power marks.

The best alternatives to magic penetration are rated as following:
★★★★★  ability power marks
★★★★  hybrid penetration
★★★  flat ap
★★  ap runes
★★  ability power runes
★★  ability power
★★  magic resist
★★  armor penetration
★★  ability power lol
★  ap league of legends

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magic penetration
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