The best replacement for line 6 spider is fender mustang.

The best alternatives to line 6 spider are rated as following:
★★★★★  fender mustang
★★★★  peavey vypyr
★★★  roland cube
★★★  marshall mg
★  peavey vyper
★  vox valvetronix
★  peavey vypyr 15
  roland micro cube

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line 6 spider
fender mustang
peavey vypyr