The best replacement for leiden is delft.

The best alternatives to leiden are rated as following:
★★★★★  delft
★★★  lijden
★★★  maastricht
★★★  utrecht
★★  haarlem
★★  groningen
★  leyden
  protein c deficiency

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Speaking about leiden, one probably shouldn't forget about protein c deficiency.

Other search terms related to leiden and their ratings are:
★★★★★ protein c deficiency
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leiden
delft
lijden