The best replacement for large cell carcinoma is small cell carcinoma.

The best alternatives to large cell carcinoma are rated as following:
★★★★★  small cell carcinoma
★★★  small cell

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No companions for large cell carcinoma have been suggested so far.
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Google Trends

Scale is based on the average worldwide traffic of large cell carcinoma in all years. Click on graph for more.
large cell carcinoma
small cell carcinoma
small cell