The best replacement for lab created is real diamonds.

The best alternatives to lab created are rated as following:
★★★★★  real diamonds
★★★★★  natural sapphire
★★★★★  natural gemstones
★★★  natural emerald
★★★  natural stones
★★★  natural diamonds
★★  simulated
★★  natural ruby
★★  natural diamond
★★  natural alexandrite
★★  simulated diamonds
★★  natural sapphires
★  natural opal
★  real rubies
★  simulated gemstones
  simulated diamond
  real emerald
  real diamond
  real sapphires

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Google Trends

Scale is based on the average worldwide traffic of lab created in all years. Click on graph for more.
lab created
real diamonds
natural sapphire