The best replacement for imageready is photoshop.

The best alternatives to imageready are rated as following:
★★★★★  photoshop
★★★  fireworks
  adobe photoshop

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Speaking about imageready, one probably shouldn't forget about photoshop.

Other search terms related to imageready and their ratings are:
★★★★★ photoshop
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Google Trends

Scale is based on the average worldwide traffic of imageready in all years. Click on graph for more.
imageready
photoshop
fireworks