The best replacement for homebrew is macports.

The best alternatives to homebrew are rated as following:
★★★★★  macports
★★  hackless
★★  commercial beer
★★  pip
★  npm
★  bower
★  modchip
★  ports
★  fink
★  apt-get
★  homebrew
★  home brew
  bootmii
  mamp
  craft beer
  northern brewer
  mod chip

Your alternative for homebrew is not listed? Suggest!
Speaking about homebrew, one probably shouldn't forget about sd card.

Other search terms related to homebrew and their ratings are:
★★★★★ sd card
★★ macports
★★ hops
★ 4.3
★ modchip
kegs
You have in mind a companion for homebrew and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of homebrew in all years. Click on graph for more.
homebrew
macports
hackless