The best replacement for hd 4650 is hd 5450.

The best alternatives to hd 4650 are rated as following:
★★★★★  hd 5450
★★★★★  9500gt
★★★★  9500 gt
★★★  nvidia geforce gt 220
★★  1gb nvidia geforce gt 220
★  hd 3850
★  gt 220
  hd 3650

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hd 4650
hd 5450
9500gt