The best replacement for harlem is brooklyn.

The best alternatives to harlem are rated as following:
★★★★★  brooklyn
★★★  bronx
★★  columbia university
★★  dream deferred
★★  compton
★  abra
★  queens
★  washington heights
★  bed stuy
  shehyee smugglaz
  apoc dictah
  gangnam
  crip walk
  boylan
  east harlem
  spanish harlem
  manhattan
  badang

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Speaking about harlem, one probably shouldn't forget about crip walk.

Other search terms related to harlem and their ratings are:
★★★★★ crip walk
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Google Trends

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harlem
brooklyn
bronx