The best replacement for gm 5.3 is ford 5.0.

The best alternatives to gm 5.3 are rated as following:
★★★★★  ford 5.0
★★★★★  ford 5.4
★★  hemi 5.7
★  5.4
  ram 5.7

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gm 5.3
ford 5.0
ford 5.4