The best replacement for focusrite saffire is motu.

The best alternatives to focusrite saffire are rated as following:
★★★★★  motu
★★★★  presonus firestudio
★★★  apogee duet
★★★  presonus firebox
★★★  motu 828
★★  rme fireface
★  motu ultralite
★  rme babyface

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focusrite saffire
motu
presonus firestudio