The best replacement for f250 is f350.

The best alternatives to f250 are rated as following:
★★★★★  f350
★★★★  chevy 2500
★★★★  f150
★★★  tundra
★★★  2500hd
★★  ram 2500
★★  2500
★  chevy 2500hd
★  dodge 2500
★  f350 srw
★  gmc 2500
★  f150 mpg
  ford f350
  f350 ride
  silverado
  excursion
  silverado 2500
  dodge ram
  chevrolet 2500hd
  toyota tundra
  dodge ram 2500
  gmc 2500hd
  raptor
  2011 f250

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f250
f350
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