The best replacement for excuse is reason.

The best alternatives to excuse are rated as following:
★★★★★  reason
★★★  explanation
★★★  justification
★★  recuse
★  forgive
★  excuse
★  sorry
★  recuse definition
★  pardon
★  apology
  pretext
  apologize
  accuse
  reasons
  acceptable reason

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Google Trends

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excuse
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