The best replacement for epidemic is outbreak.

The best alternatives to epidemic are rated as following:
★★★★★  outbreak
★★★★★  endemic
★★★★  pandemic
★★  pandemic definition
★  myth
★  pandemic worse
★  plague
★  infidel
★  pandemic differences
★  pandemic difference
  common source
  sporadic
  aids pandemic
  endemic definition
  virulence
  epidemic
  endemic disease

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Google Trends

Scale is based on the average worldwide traffic of epidemic in all years. Click on graph for more.
epidemic
outbreak
endemic