The best replacement for effusion is edema.

The best alternatives to effusion are rated as following:
★★★★★  edema
★★★★★  diffusion
★★★  swelling
★★★  infiltrate
★★★  consolidation
★★  pulmonary edema
★★  pneumonia
★★  pneumothorax
★★  empyema
★★  tamponade
★  cardiac tamponade
★  synovitis
★  pleural
★  bursitis
★  atelectasis
★  thickening
★  hemarthrosis
★  transudate
  pericardial thickening
  pleurisy
  pericardial effusion
  pleural thickening
  diffusion definition
  diffusion chemistry
  pleural effusion
  ascites
  serous otitis media
  diffusion faster
  tb effusion
  soft tissue swelling
  exudative effusion

Your alternative for effusion is not listed? Suggest!
Speaking about effusion, one probably shouldn't forget about tamponade.

Other search terms related to effusion and their ratings are:
★★★★★ tamponade
★★★ pneumonia
★★★ synovitis
★★ lung cancer
★★ atelectasis
★★ otitis media
★ synovitis knee
★ compressive atelectasis
★ pericarditis
★ ovarian cancer
★ ascites
★ consolidation
chest tube
cardiac tamponade
chf
empyema
arthritis
evidence of synovitis
basilar atelectasis
pleural effusion
thoracentesis
pulmonary embolism
congestive heart failure
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Google Trends

Scale is based on the average worldwide traffic of effusion in all years. Click on graph for more.
effusion
edema
diffusion