The best replacement for e5645 is x5650.

The best alternatives to e5645 are rated as following:
★★★★★  x5650
★★★★★  e5-2620
★★★★★  e5620
★★★★  e5-2630
★★★★  e5-2640
★★★★  e5649
★★★  e5-2609
★★★  e5 2420
★★★  e5-2430
★★★  e5640
★★  e5520
★★  e5-2440
★  e5540
★  w3565

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e5645
x5650
e5-2620