The best replacement for e5-2643 is e5-1620.

The best alternatives to e5-2643 are rated as following:
★★★★★  e5-1620
★★★★  x5687
★★★  e5-2690
★★★  e5-2640
★★  e5-2667
★★  e5-2665
★  e5-2687w
★  e5-1650
  e5-2637

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e5-2643
e5-1620
x5687