The best replacement for diphenhydramine is doxylamine.

The best alternatives to diphenhydramine are rated as following:
★★★★★  doxylamine
★★★  loratadine
★★★  doxylamine succinate
★★  chlorpheniramine
★★  cetirizine
★★  melatonin
★★  dextromethorphan
★  dimenhydrinate
★  ambien
★  benadryl
★  phenylephrine
★  dxm
★  diphenhydramine hcl
★  pseudoephedrine
★  hydroxyzine
★  diphenhydramine hydrochloride
  dramamine
  fexofenadine
  diphenhydramine citrate
  chlorpheniramine maleate
  cetirizine hydrochloride
  hydrocortisone
  zolpidem
  zopiclone
  benztropine
  diphenhydramine hci

Your alternative for diphenhydramine is not listed? Suggest!
Speaking about diphenhydramine, one probably shouldn't forget about pseudoephedrine.

Other search terms related to diphenhydramine and their ratings are:
★★★★★ pseudoephedrine
★★ phenylephrine
★★ dextromethorphan
★★ loratadine
★ dxm
You have in mind a companion for diphenhydramine and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of diphenhydramine in all years. Click on graph for more.
diphenhydramine
doxylamine
loratadine