The best replacement for destruction is affliction.

The best alternatives to destruction are rated as following:
★★★★★  affliction
★★★  demonology
★★★  affliction warlock
★★  affliction 5.4
★★  conjuration skyrim
★  affliction pvp
★  creation
★  archery skyrim
★  archery
★  demonology 5.4
★  dx
★  peace
★  demonology warlock
★  demonology leveling
  ruin
  destruction
  deconstruction
  order
  grave digger
  affliction mop
  excision
  kronik
  affliction 4.3
  conservation
  kreator
  hardy boyz
  conjuration
  construction
  affliction 5.2

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