The best replacement for desoximetasone is desonide.

The best alternatives to desoximetasone are rated as following:
★★★★★  desonide
★★★  clobetasol
★★★  fluocinonide
★  triamcinolone
★  clobetasol propionate

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No companions for desoximetasone have been suggested so far.
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Google Trends

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desoximetasone
desonide
clobetasol