The best replacement for denosumab is zometa.

The best alternatives to denosumab are rated as following:
★★★★★  zometa
★★★★  bisphosphonates
★★★★  zoledronic acid
★★★  alendronate
★★  reclast
★★  romosozumab
★  forteo

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Google Trends

Scale is based on the average worldwide traffic of denosumab in all years. Click on graph for more.
denosumab
zometa
bisphosphonates