The best replacement for crest syndrome is systemic sclerosis.

The best alternatives to crest syndrome are rated as following:
★★★★★  systemic sclerosis

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Speaking about crest syndrome, one probably shouldn't forget about scleroderma.

Other search terms related to crest syndrome and their ratings are:

★★★★★ scleroderma
limited scleroderma
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crest syndrome
systemic sclerosis