The best replacement for cherrypy is django.

The best alternatives to cherrypy are rated as following:
★★★★★  django
★★★★  flask
★★★  bottle
★★★  paste
★★  twisted
★★  web2py
★★  gunicorn
★  web.py
★  pylons
★  werkzeug
  webpy
  uwsgi

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Google Trends

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cherrypy
django
flask