The best replacement for canon 100 400 is sigma 50 500.

The best alternatives to canon 100 400 are rated as following:
★★★★★  sigma 50 500
★★★  400
★★★  sigma 150 500
★★  nikon 80 400
★★  sigma 80 400
★  sigma 120 400
★  canon 400
★  sigma 150-500
★  sigma 100 300

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Speaking about canon 100 400, one probably shouldn't forget about teleconverter.

Other search terms related to canon 100 400 and their ratings are:
★★★★★ teleconverter
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