The best replacement for cannons is machine guns.

The best alternatives to cannons are rated as following:
★★★★★  machine guns
★★★  dual heavy cannons
★★★  canons
★★★  outlaws
★★★  lizards
★★★  archer towers
★★  beams sto
★  turrets
★  ieee cannons
★  chesapeake bayhawks
★  south melbourne
  modern cannons

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Speaking about cannons, one probably shouldn't forget about ega.

Other search terms related to cannons and their ratings are:
★★★★★ ega
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cannons
machine guns
dual heavy cannons