The best replacement for bivalirudin is heparin.

The best alternatives to bivalirudin are rated as following:
★★★★★  heparin
★★★  argatroban
★★  eptifibatide
★  unfractionated heparin
★  lepirudin
  abciximab

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No companions for bivalirudin have been suggested so far.
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Google Trends

Scale is based on the average worldwide traffic of bivalirudin in all years. Click on graph for more.
bivalirudin
heparin
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