The best replacement for attack damage is attack speed.

The best alternatives to attack damage are rated as following:
★★★★★  attack speed
★★★★★  armor pen
★★★★★  armor pen runes
★★★★  scaling attack damage
★★★★  ability power
★★★★  armor pen quints
★★  armor penetration quints
★★  attack speed runes
★★  armor penetration marks
★★  physical damage
★  armor penetration
★  ability power lol
★  armor pen lol
★  critical damage
★  armor penetration league of legends
★  attack damage per level
★  ability power ezreal
★  armor pen season 3
★  armour pen runes
  armor penetration lol
  armor pen vayne
  armor lol

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