The best replacement for apm 2.5 is naza.

The best alternatives to apm 2.5 are rated as following:
★★★★★  naza
★★★★  multiwii
★★★  dji naza
★★  multiwii pro
★  cc3d

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Speaking about apm 2.5, one probably shouldn't forget about tbs discovery.

Other search terms related to apm 2.5 and their ratings are:
★★★★★ tbs discovery
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apm 2.5
naza
multiwii