The best replacement for apixaban is warfarin.

The best alternatives to apixaban are rated as following:
★★★★★  warfarin
★★★★★  rivaroxaban
★★  pradaxa
★★  dabigatran
★★  edoxaban
★  rivaroxaban and dabigatran

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No companions for apixaban have been suggested so far.
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apixaban
warfarin
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