The best replacement for ap bio is ap chem.

The best alternatives to ap bio are rated as following:
★★★★★  ap chem
★★★★★  ap physics
★★  apes
★★  ap euro
★★  ap stats
★  physics honors
★  ib bio
★  physics
★  sat bio
★  college bio
★  chem
★  ap physics b
★  apush
★  anatomy
  honors bio
  anatomy and physiology
  ap chemistry
  honors physics

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