The best replacement for afrin is sudafed.

The best alternatives to afrin are rated as following:
★★★★★  sudafed
★★★★★  flonase
★★★★  nasonex
★★★★  zicam
★★★  neo synephrine
★★★  sinex
★★  nasacort
★★  otrivin
★  vicks
★  fluticasone propionate
★  astelin
★  saline nasal spray
★  neo-synephrine
★  dristan
★  mucinex
★  4 way
  mucinex nasal spray
  nasalcrom
  vicks sinex
  4-way nasal spray
  neti pot
  astepro
  4-way
  nasalx

Your alternative for afrin is not listed? Suggest!
Speaking about afrin, one probably shouldn't forget about flonase.

Other search terms related to afrin and their ratings are:
★★★★★ flonase
★★★★★ nasonex
rebound
You have in mind a companion for afrin and it is not yet here? Propose!



Google Trends

Scale is based on the average worldwide traffic of afrin in all years. Click on graph for more.
afrin
sudafed
flonase