The best replacement for ab initio is informatica.

The best alternatives to ab initio are rated as following:
★★★★★  informatica
★★★  datastage
★★★  de novo
★★  talend
★★  semi empirical
  semi-empirical
  data stage

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Speaking about ab initio, one probably shouldn't forget about data profiling.

Other search terms related to ab initio and their ratings are:
★★★★★ data profiling
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