The best replacement for 721 is helvetica.

The best alternatives to 721 are rated as following:
★★★★★  helvetica
★★★★★  823
★★★★  729
★★★  stans flow
★★★  921
★★  725
★★  725 leader
★★  521
★  621
★  ztr flow
  unknown lv1
  section 351

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Google Trends

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721
helvetica
823