The best replacement for 5fu is xeloda.

The best alternatives to 5fu are rated as following:
★★★★★  xeloda
★  folfox

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Speaking about 5fu, one probably shouldn't forget about leucovorin.

Other search terms related to 5fu and their ratings are:
★★★★★ leucovorin
★ oxaliplatin
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Google Trends

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5fu
xeloda
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