The best replacement for 45 is 9mm.

The best alternatives to 45 are rated as following:
★★★★★  9mm
★★★★  40
★★★★  357
★★★  10mm
★★  9
★  40 cal
★  45 acp
★  357 sig
★  44 mag
★  33
★  44 magnum
★  33 rpm
★  44
★  78
★  40 caliber
★  9mm 1911
  9mm stopping power
  38 super
  40 handgun
  380
  40 recoil
  357 more powerful
  9mm energy
  78 records
  rj 48
  10 mm
  .40
  40 s&w
  357 mag
  glock 21
  38 special
  9mm ballistics
  .357
  5.56
  40 stopping power
  33 record
  .40 caliber
  xds 9mm
  .40 which is better
  9mm handgun
  xd 45
  9mm recoil
  45acp
  glock 30
  1911
  .357 magnum
  9mm pistol
  lp
  357 magnum
  glock 36
  .44 magnum
  glock 45
  hk usp 45
  acp 45
  rj 11
  remeron 30
  hk45
  38
  14 54
  40 ballistics
  xdm 45
  mark iii

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45
9mm
40