The best replacement for 25i is 25c.

The best alternatives to 25i are rated as following:
★★★★★  25c
★★★★  25b
★★★  acid
★★  shrooms
★★  2cb
★★  25p
★★  2ci
★★  50i
★★  2ce
★  mescaline
★  lsd
★  50p
  25d

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25i
25c
25b