The best replacement for 22lr is 223.

The best alternatives to 22lr are rated as following:
★★★★★  223
★★★★  22 mag
★★★★  9mm
★★★★  17hmr
★★★★  22 wmr
★★★  25acp
★★★  22
★★  22 magnum
★★  380
★  22mag
★  17 hmr
★  25 acp
★  5.56
★  22 hornet
★  17
★  22 mini mag
★  22-250
★  22 short
★  22wmr
★  380 acp
★  air rifle
  38 special
  pellet gun
  9mm carbine
  223 ammo
  17 mach 2
  22 mag ammo
  17hm2
  32 acp
  223 rem
  22 long
  mag
  .223

Your alternative for 22lr is not listed? Suggest!
Speaking about 22lr, one probably shouldn't forget about slide fire.

Other search terms related to 22lr and their ratings are:
★★★★★ slide fire
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22lr
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