The best replacement for 22 45 is mark iii.

The best alternatives to 22 45 are rated as following:
★★★★★  mark iii
★★★  browning buckmark
★★  mkiii
★★  walther p22
★  mark 3
★  buckmark
★  ruger mkiii
★  sig mosquito
★  sr22
  mk3
  browning buck mark

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22 45
mark iii
browning buckmark